Multiple Choice Questions

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Chapter 5, Question 1.


1. A patient with multiple myeloma has increased protein levels in his serum and high protein levels in his urine. Both serum and urine samples are run on a protein gel electrophoresis. Given that the protein in his urine is a Bence Jones protein only, you would expect which of the following?

a. the electrophoretic patterns to show sharp spikes in identical locations for both the serum and urine.

b. the electrophoretic patterns to show sharp spikes in different locations in the serum and urine.

c. the urine electrophoresis to show a sharp spike but the serum to show a broad band in the gamma region.

d. the urine electrophoresis to show a broad band in the gamma region but the serum to show a sharp spike.