Multiple Choice Questions

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Chapter 4, Question 1.


1. You are a laboratory worker involved in vaccine development for a specific pathogen. Success would be demonstrated when you can show that the candidate vaccine elicits an immune response in vaccinated individuals such that infection cannot be established when the individual is subsequently exposed to the pathogen. It is known that there are neutralizing antibodies directed against a particular surface molecule in individuals who have recovered from infection with the pathogen under study. However, when that molecule was isolated and injected into rabbits as an antigen, it failed to elicit an immune response. The goal of your project is to modify the antigen to do which of the following?

a. to become an immunogen.

b. to overcome tolerance.

c. to overcome autoimmunity.

d. to ensure that it can bind to T cells as well as antibody.

e. to become a carrier.